منابع مشابه
Adipokines promote chronic kidney disease.
The rapid growth in obesity worldwide contributes to an increase in metabolic syndrome and obesity-related kidney disease with an enhanced increased risk for chronic kidney disease, finally progressing to end-stage renal disease. Adipose tissue is a highly active endocrine organ secreting numerous factors that contribute to renal and cardiovascular complications. In renal damage, various adipok...
متن کاملFunctions of Adipose Tissue and Adipokines in Health and Disease
Francisca Lago1, Rodolfo Gómez2, Javier Conde2, Morena Scotece2, Carlos Dieguez3 and Oreste Gualillo2 1SERGAS Santiago University Clinical Hospital, Research Laboratory 7 (Molecular and Cellular Cardiology), Santiago de Compostela, 2SERGAS Santiago University Clinical Hospital, Research Laboratory 9 (NEIRID LAB, Laboratory of Neuro Endocrine Interactions in Rheumatology and Inflammatory Disease...
متن کاملAdipokines and Non-Alcoholic Fatty Liver Disease: Multiple Interactions
Accumulating evidence links obesity with low-grade inflammation which may originate from adipose tissue that secretes a plethora of pro- and anti-inflammatory cytokines termed adipokines. Adiponectin and leptin have evolved as crucial signals in many obesity-related pathologies including non-alcoholic fatty liver disease (NAFLD). Whereas adiponectin deficiency might be critically involved in th...
متن کاملAdipokines at the crossroad between obesity and cardiovascular disease.
Obesity, and especially excessive visceral adipose tissue accumulation, is considered as a low-grade inflammatory state that is responsible for adipocyte dysfunction and associated metabolic disorders. Adipose tissue displays endocrine functions by releasing pro- or anti-inflammatory bioactive molecules named adipokines. An altered expression of these molecules, provoked by obesity or adipocyte...
متن کاملAdipokines as a link between obesity and chronic kidney disease.
Adipocytes secrete a number of bioactive adipokines that activate a variety of cell signaling pathways in central and peripheral tissues. Obesity is associated with the altered production of many adipokines and is linked to a number of pathologies. As an increase in body weight is directly associated with an increased risk for developing chronic kidney disease (CKD), there is significant intere...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology and Therapeutics
سال: 2006
ISSN: 0269-2813,1365-2036
DOI: 10.1111/j.1365-2036.2006.03030.x